The influence of micronutrients on olfactory dysfunction associated with COVID-19 and long COVID
, S., Next Research, doi:10.1016/j.nexres.2026.101727, Apr 2026
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Review of the influence of micronutrients on olfactory dysfunction associated with COVID-19 and long COVID. Author investigates how dietary supplements like vitamins A, B, C, D, E, zinc, and alpha-lipoic acid can help restore the sense of smell by reducing localized inflammation and supporting neuroregeneration in the olfactory epithelium.
1.
Younes, S., The influence of micronutrients on olfactory dysfunction associated with COVID-19 and long COVID, Next Research, doi:10.1016/j.nexres.2026.101727.
2.
Al-Khrasani et al., Do vitamins halt the COVID-19-evoked pro-inflammatory cytokines involved in the development of neuropathic pain?, Biomedicine & Pharmacotherapy, doi:10.1016/j.biopha.2025.118346.
3.
Sanduzzi Zamparelli et al., Immune-Boosting and Antiviral Effects of Antioxidants in COVID-19 Pneumonia: A Therapeutic Perspective, Life, doi:10.3390/life15010113.
4.
DiGuilio et al., Micronutrient Improvement of Epithelial Barrier Function in Various Disease States: A Case for Adjuvant Therapy, International Journal of Molecular Sciences, doi:10.3390/ijms23062995.
5.
Stephensen et al., Vitamin A in resistance to and recovery from infection: relevance to SARS-CoV2, British Journal of Nutrition, doi:10.1017/S0007114521000246.
Younes et al., 8 Apr 2026, peer-reviewed, 1 author.
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"DOI": "10.1016/S0140-6736(20)30154-9",
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"author": "To",
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"year": "2024"
},
{
"DOI": "10.1080/07853890.2022.2076901",
"article-title": "Van den Heede K. Pathophysiology and mechanism of long COVID: a comprehensive review",
"author": "Castanares-Zapatero",
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"author": "Wang",
"doi-asserted-by": "crossref",
"journal-title": "J. Biomed. Inform.",
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"DOI": "10.1007/s10072-021-05611-6",
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"author": "Ercoli",
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"first-page": "4921",
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"volume": "42",
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},
{
"DOI": "10.1016/j.clnesp.2023.03.013",
"article-title": "The association between dietary intakes of zinc, vitamin C and COVID-19 severity and related symptoms: a cross-sectional study",
"author": "Asoudeh",
"doi-asserted-by": "crossref",
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"journal-title": "Clin. Nutr. ESPEN",
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"volume": "55",
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{
"DOI": "10.1186/1749-8104-8-13",
"article-title": "Retinoic acid regulates olfactory progenitor cell fate and differentiation",
"author": "Paschaki",
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"key": "10.1016/j.nexres.2026.101727_bib0010",
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"DOI": "10.1002/lary.23405",
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{
"DOI": "10.1007/s12070-021-02749-9",
"article-title": "Comparison of the healing effect of nasal saline irrigation with triamcinolone acetonide versus nasal saline irrigation alone in COVID-19 related olfactory dysfunction: a randomized controlled study",
"author": "Yildiz",
"doi-asserted-by": "crossref",
"first-page": "3022",
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"journal-title": "Indian J. Otolaryngol. Head. Neck. Surg.",
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{
"DOI": "10.1126/sciadv.abc5801",
"article-title": "Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia",
"author": "Brann",
"doi-asserted-by": "crossref",
"issue": "31",
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{
"DOI": "10.1021/acschemneuro.0c00249",
"article-title": "Proinflammatory cytokines in the olfactory mucosa result in COVID-19 induced anosmia",
"author": "Torabi",
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"first-page": "1909",
"issue": "13",
"journal-title": "ACS Chem. Neurosci.",
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{
"DOI": "10.1523/JNEUROSCI.4507-09.2010",
"article-title": "A genetic model of chronic rhinosinusitis-associated olfactory inflammation reveals reversible functional impairment and dramatic neuroepithelial reorganization",
"author": "Lane",
"doi-asserted-by": "crossref",
"first-page": "2324",
"issue": "6",
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{
"DOI": "10.1073/pnas.1620664114",
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"author": "Chen",
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"first-page": "8089",
"issue": "30",
"journal-title": "Proc. Natl. Acad. Sci. U.S.A.",
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"year": "2017"
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{
"DOI": "10.1126/scitranslmed.add0484",
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"author": "Finlay",
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{
"DOI": "10.1038/s41467-025-64778-0",
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"author": "Reddy",
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"first-page": "9494",
"issue": "1",
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"volume": "16",
"year": "2025"
},
{
"DOI": "10.1186/s12974-022-02657-x",
"article-title": "Effects of nasal inflammation on the olfactory bulb",
"author": "LaFever",
"doi-asserted-by": "crossref",
"first-page": "294",
"issue": "1",
"journal-title": "J. Neuroinflammation",
"key": "10.1016/j.nexres.2026.101727_bib0025",
"volume": "19",
"year": "2022"
},
{
"DOI": "10.1038/sj.bjp.0706736",
"article-title": "How corticosteroids control inflammation: quintiles prize lecture 2005",
"author": "Barnes",
"doi-asserted-by": "crossref",
"first-page": "245",
"issue": "3",
"journal-title": "Br. J. Pharmacol.",
"key": "10.1016/j.nexres.2026.101727_bib0026",
"volume": "148",
"year": "2006"
},
{
"DOI": "10.4193/Rhin22.483",
"article-title": "Position paper on olfactory dysfunction: 2023",
"author": "Whitcroft",
"doi-asserted-by": "crossref",
"first-page": "1",
"issue": "33",
"journal-title": "Rhinology",
"key": "10.1016/j.nexres.2026.101727_bib0027",
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{
"DOI": "10.1007/s11882-024-01182-6",
"article-title": "Treatment of COVID-19 associated olfactory dysfunction: a systematic review",
"author": "Bischoff",
"doi-asserted-by": "crossref",
"first-page": "2",
"issue": "1",
"journal-title": "Curr. Allergy Asthma Rep.",
"key": "10.1016/j.nexres.2026.101727_bib0028",
"volume": "25",
"year": "2024"
},
{
"DOI": "10.1001/jamaoto.2014.1675",
"article-title": "Risk factors for hazardous events in olfactory-impaired patients",
"author": "Pence",
"doi-asserted-by": "crossref",
"first-page": "951",
"issue": "10",
"journal-title": "JAMA Otolaryngol. Head. Neck. Surg.",
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"volume": "140",
"year": "2014"
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{
"article-title": "Olfaction and emotion",
"author": "Ehrlichman",
"first-page": "410",
"key": "10.1016/j.nexres.2026.101727_bib0030",
"series-title": "Science of Olfaction",
"year": "1992"
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{
"article-title": "Consequences of olfactory loss and adopted coping strategies",
"author": "Blomqvist",
"first-page": "189",
"issue": "4",
"journal-title": "Rhinology",
"key": "10.1016/j.nexres.2026.101727_bib0031",
"volume": "42",
"year": "2004"
},
{
"DOI": "10.1093/chemse/bjt072",
"article-title": "Olfactory disorders and quality of life–an updated review",
"author": "Croy",
"doi-asserted-by": "crossref",
"first-page": "185",
"issue": "3",
"journal-title": "Chem. Senses",
"key": "10.1016/j.nexres.2026.101727_bib0032",
"volume": "39",
"year": "2014"
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{
"article-title": "Diet and inflammatory bowel disease",
"author": "Knight-Sepulveda",
"first-page": "511",
"issue": "8",
"journal-title": "Gastroenterol. Hepatol.",
"key": "10.1016/j.nexres.2026.101727_bib0033",
"volume": "11",
"year": "2015"
},
{
"DOI": "10.3748/wjg.14.4280",
"article-title": "Role of cytokines in inflammatory bowel disease",
"author": "Sanchez-Munoz",
"doi-asserted-by": "crossref",
"first-page": "4280",
"issue": "27",
"journal-title": "World J. Gastroenterol.",
"key": "10.1016/j.nexres.2026.101727_bib0034",
"volume": "14",
"year": "2008"
},
{
"DOI": "10.7861/clinmed.2020-0301",
"article-title": "Does vitamin D deficiency increase the severity of COVID-19?",
"author": "Weir",
"doi-asserted-by": "crossref",
"first-page": "e107",
"issue": "4",
"journal-title": "Clin. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0035",
"volume": "20",
"year": "2020"
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{
"DOI": "10.1016/j.jada.2011.02.003",
"article-title": "Vitamin C status is related to proinflammatory responses and impaired vascular endothelial function in healthy, college-aged lean and obese men",
"author": "Mah",
"doi-asserted-by": "crossref",
"first-page": "737",
"issue": "5",
"journal-title": "J. Am. Diet. Assoc.",
"key": "10.1016/j.nexres.2026.101727_bib0036",
"volume": "111",
"year": "2011"
},
{
"DOI": "10.1016/j.freeradbiomed.2011.05.017",
"article-title": "Vitamins C and E: beneficial effects from a mechanistic perspective",
"author": "Traber",
"doi-asserted-by": "crossref",
"first-page": "1000",
"issue": "5",
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"volume": "51",
"year": "2011"
},
{
"article-title": "The dual role of toll-like receptors in COVID-19: Balancing protective immunity and immunopathogenesis",
"author": "Behzadi",
"issue": "Pt 2",
"journal-title": "Int. J. Biol. Macromol.",
"key": "10.1016/j.nexres.2026.101727_bib0038",
"volume": "284",
"year": "2025"
},
{
"DOI": "10.3389/fphar.2024.1388348",
"article-title": "Vitamin D level in COVID-19 patients has positive correlations with autophagy and negative correlations with disease severity",
"author": "Dong",
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"key": "10.1016/j.nexres.2026.101727_bib0039",
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"DOI": "10.3390/biomedicines12092085",
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"article-title": "Provitamin A metabolism and functions in mammalian biology",
"author": "von Lintig",
"doi-asserted-by": "crossref",
"issue": "5",
"journal-title": "Am. J. Clin. Nutr.",
"key": "10.1016/j.nexres.2026.101727_bib0042",
"volume": "96",
"year": "2012"
},
{
"DOI": "10.3390/cancers12051169",
"article-title": "All-trans retinoic acid stimulates viral mimicry, interferon responses and antigen presentation in breast-cancer cells",
"author": "Bolis",
"doi-asserted-by": "crossref",
"first-page": "1169",
"issue": "5",
"journal-title": "Cancers",
"key": "10.1016/j.nexres.2026.101727_bib0043",
"volume": "12",
"year": "2020"
},
{
"article-title": "Znaczenie niedoboru witaminy A dla patologii i immunologii zakazeń wirusowych [Importance of vitamin A deficiency in pathology and immunology of viral infections]",
"author": "Kańtoch",
"first-page": "385",
"issue": "4",
"journal-title": "Rocz. Panstw. Zakl. Hig.",
"key": "10.1016/j.nexres.2026.101727_bib0044",
"volume": "53",
"year": "2002"
},
{
"DOI": "10.1128/CMR.18.3.446-464.2005",
"article-title": "Effects of vitamin a supplementation on immune responses and correlation with clinical outcomes",
"author": "Villamor",
"doi-asserted-by": "crossref",
"first-page": "446",
"issue": "3",
"journal-title": "Clin. Microbiol. Rev.",
"key": "10.1016/j.nexres.2026.101727_bib0045",
"volume": "18",
"year": "2005"
},
{
"DOI": "10.1016/S0083-6729(06)75013-0",
"article-title": "Effects of vitamins, including vitamin A, on HIV/AIDS patients",
"author": "Mehta",
"doi-asserted-by": "crossref",
"first-page": "355",
"journal-title": "Vitam. Horm.",
"key": "10.1016/j.nexres.2026.101727_bib0046",
"volume": "75",
"year": "2007"
},
{
"DOI": "10.1177/0194599811425019",
"article-title": "Evaluation of factors concerning the olfaction using the Sniffin' Sticks test",
"author": "Orhan",
"doi-asserted-by": "crossref",
"first-page": "240",
"issue": "2",
"journal-title": "Otolaryngol. Head. Neck. Surg.",
"key": "10.1016/j.nexres.2026.101727_bib0047",
"volume": "146",
"year": "2012"
},
{
"DOI": "10.1007/s00405-018-5248-1",
"article-title": "Updated Sniffin' Sticks normative data based on an extended sample of 9139 subjects",
"author": "Oleszkiewicz",
"doi-asserted-by": "crossref",
"first-page": "719",
"issue": "3",
"journal-title": "Eur. Arch. Otorhinolaryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0048",
"volume": "276",
"year": "2019"
},
{
"DOI": "10.1001/archotol.1962.00740040122008",
"article-title": "Treatment of uncomplicated anosmia by vitamin A",
"author": "DUNCAN",
"doi-asserted-by": "crossref",
"first-page": "116",
"journal-title": "Arch. Otolaryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0049",
"volume": "75",
"year": "1962"
},
{
"DOI": "10.1016/j.tins.2022.11.003",
"article-title": "Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms",
"author": "Butowt",
"doi-asserted-by": "crossref",
"first-page": "75",
"issue": "1",
"journal-title": "Trends. Neurosci.",
"key": "10.1016/j.nexres.2026.101727_bib0050",
"volume": "46",
"year": "2023"
},
{
"DOI": "10.1016/0300-483X(89)90161-3",
"article-title": "Comparative assessment of the toxicology of vitamin A and retinoids in man",
"author": "Biesalski",
"doi-asserted-by": "crossref",
"first-page": "117",
"issue": "2",
"journal-title": "Toxicology",
"key": "10.1016/j.nexres.2026.101727_bib0051",
"volume": "57",
"year": "1989"
},
{
"DOI": "10.1007/s00405-017-4576-x",
"article-title": "Intranasal vitamin A is beneficial in post-infectious olfactory loss",
"author": "Hummel",
"doi-asserted-by": "crossref",
"first-page": "2819",
"issue": "7",
"journal-title": "Eur. Arch. Otorhinolaryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0052",
"volume": "274",
"year": "2017"
},
{
"DOI": "10.1002/lary.23405",
"article-title": "Olfactory function in patients with postinfectious and posttraumatic smell disorders before and after treatment with vitamin A: a double-blind, placebo-controlled, randomized clinical trial",
"author": "Reden",
"doi-asserted-by": "crossref",
"first-page": "1906",
"issue": "9",
"journal-title": "Laryngoscope",
"key": "10.1016/j.nexres.2026.101727_bib0053",
"volume": "122",
"year": "2012"
},
{
"article-title": "Impairment of taste and olfaction in patients with cirrhosis: the role of vitamin A",
"author": "Garrett-Laster",
"first-page": "203",
"issue": "3",
"journal-title": "Hum. Nutr. Clin. Nutr.",
"key": "10.1016/j.nexres.2026.101727_bib0054",
"volume": "38",
"year": "1984"
},
{
"DOI": "10.3390/brainsci13071014",
"article-title": "A pilot study of short-course oral vitamin A and aerosolised diffuser olfactory training for the treatment of smell loss in long COVID",
"author": "Chung",
"doi-asserted-by": "crossref",
"first-page": "1014",
"issue": "7",
"journal-title": "Brain Sci.",
"key": "10.1016/j.nexres.2026.101727_bib0055",
"volume": "13",
"year": "2023"
},
{
"DOI": "10.1126/science.6251551",
"article-title": "Photosynthesis of previtamin D3 in human skin and the physiologic consequences",
"author": "Holick",
"doi-asserted-by": "crossref",
"first-page": "203",
"issue": "4466",
"journal-title": "Science",
"key": "10.1016/j.nexres.2026.101727_bib0056",
"volume": "210",
"year": "1980"
},
{
"author": "Asif",
"key": "10.1016/j.nexres.2026.101727_bib0057"
},
{
"article-title": "Clothing prevents ultraviolet-B radiation-dependent photosynthesis of vitamin D3",
"author": "Matsuoka",
"first-page": "1099",
"issue": "4",
"journal-title": "J. Clin. Endocrinol. Metab.",
"key": "10.1016/j.nexres.2026.101727_bib0058",
"volume": "75",
"year": "1992"
},
{
"DOI": "10.1210/jcem-64-6-1165",
"article-title": "Sunscreens suppress cutaneous vitamin D3 synthesis",
"author": "Matsuoka",
"doi-asserted-by": "crossref",
"first-page": "1165",
"issue": "6",
"journal-title": "J. Clin. Endocrinol. Metab.",
"key": "10.1016/j.nexres.2026.101727_bib0059",
"volume": "64",
"year": "1987"
},
{
"DOI": "10.1016/j.jcm.2011.06.006",
"article-title": "A possible correlation between vitamin D deficiency and loss of smell: 2 case reports",
"author": "Kruse",
"doi-asserted-by": "crossref",
"first-page": "310",
"issue": "4",
"journal-title": "J. Chiropr. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0060",
"volume": "10",
"year": "2011"
},
{
"DOI": "10.1016/j.jsbmb.2018.12.010",
"article-title": "Daily oral dosing of vitamin D3 using 5000 TO 50,000 international units a day in long-term hospitalized patients: Insights from a seven year experience",
"author": "McCullough",
"doi-asserted-by": "crossref",
"first-page": "228",
"journal-title": "J. Steroid. Biochem. Mol. Biol.",
"key": "10.1016/j.nexres.2026.101727_bib0061",
"volume": "189",
"year": "2019"
},
{
"DOI": "10.1523/JNEUROSCI.21-01-00098.2001",
"article-title": "Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons",
"author": "Brewer",
"doi-asserted-by": "crossref",
"first-page": "98",
"issue": "1",
"journal-title": "J. Neurosci.",
"key": "10.1016/j.nexres.2026.101727_bib0062",
"volume": "21",
"year": "2001"
},
{
"DOI": "10.1016/S0304-3940(03)00303-3",
"article-title": "Eyles DW. 1,25-dihydroxyvitamin D3 induces nerve growth factor, promotes neurite outgrowth and inhibits mitosis in embryonic rat hippocampal neurons",
"author": "Brown",
"doi-asserted-by": "crossref",
"first-page": "139",
"issue": "2",
"journal-title": "Neurosci. Lett.",
"key": "10.1016/j.nexres.2026.101727_bib0063",
"volume": "343",
"year": "2003"
},
{
"DOI": "10.1016/S0028-3908(01)00009-0",
"article-title": "Protective effects of 1 alpha,25-(OH)(2)D(3) against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture",
"author": "Ibi",
"doi-asserted-by": "crossref",
"first-page": "761",
"issue": "6",
"journal-title": "Neuropharmacology",
"key": "10.1016/j.nexres.2026.101727_bib0064",
"volume": "40",
"year": "2001"
},
{
"DOI": "10.1111/j.1600-0404.1975.tb01358.x",
"article-title": "Myopathy and neuropathy associated with osteomalacia",
"author": "Skaria",
"doi-asserted-by": "crossref",
"first-page": "37",
"issue": "1",
"journal-title": "Acta Neurol. Scand.",
"key": "10.1016/j.nexres.2026.101727_bib0065",
"volume": "51",
"year": "1975"
},
{
"DOI": "10.5152/B-ENT.2021.21041",
"article-title": "Effect of vitamin D on olfactory function",
"author": "Baki",
"doi-asserted-by": "crossref",
"first-page": "86",
"issue": "2",
"journal-title": "B-ENT",
"key": "10.1016/j.nexres.2026.101727_bib0066",
"volume": "17",
"year": "2021"
},
{
"DOI": "10.3122/jabfm.2009.06.090037",
"article-title": "Vitamin D: an evidence-based review",
"author": "Kulie",
"doi-asserted-by": "crossref",
"first-page": "698",
"issue": "6",
"journal-title": "J. Am. Board. Fam. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0067",
"volume": "22",
"year": "2009"
},
{
"DOI": "10.1111/nan.12020",
"article-title": "Review: the role of vitamin D in nervous system health and disease",
"author": "DeLuca",
"doi-asserted-by": "crossref",
"first-page": "458",
"issue": "5",
"journal-title": "Neuropathol. Appl. Neurobiol.",
"key": "10.1016/j.nexres.2026.101727_bib0068",
"volume": "39",
"year": "2013"
},
{
"DOI": "10.1034/j.1600-0404.2002.1c031.x",
"article-title": "Reversible peripheral neuropathy in idiopathic hypoparathyroidism",
"author": "Goswami",
"doi-asserted-by": "crossref",
"first-page": "128",
"issue": "2",
"journal-title": "Acta Neurol. Scand.",
"key": "10.1016/j.nexres.2026.101727_bib0069",
"volume": "105",
"year": "2002"
},
{
"DOI": "10.1111/pai.13341",
"article-title": "Serum vitamin D level is associated with smell dysfunction independently of aeroallergen sensitization, nasal obstruction, and the presence of allergic rhinitis in children",
"author": "Shin",
"doi-asserted-by": "crossref",
"first-page": "116",
"issue": "1",
"journal-title": "Pediatr. Allergy Immunol.",
"key": "10.1016/j.nexres.2026.101727_bib0070",
"volume": "32",
"year": "2021"
},
{
"DOI": "10.1007/s00405-017-4635-3",
"article-title": "Vit D deficiency is a possible risk factor in ARS",
"author": "Elbistanlı",
"doi-asserted-by": "crossref",
"first-page": "3391",
"journal-title": "Eur. Arch. Otorhinolaryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0071",
"volume": "274",
"year": "2017"
},
{
"DOI": "10.3390/nu12040984",
"article-title": "Age-related smell and taste impairments and vitamin D associations in the U.S. adults national health and nutrition examination survey",
"author": "Bigman",
"doi-asserted-by": "crossref",
"first-page": "984",
"issue": "4",
"journal-title": "Nutrients",
"key": "10.1016/j.nexres.2026.101727_bib0072",
"volume": "12",
"year": "2020"
},
{
"DOI": "10.1016/j.tins.2019.01.003",
"article-title": "Vitamin D in synaptic plasticity, cognitive function, and neuropsychiatric illness",
"author": "Mayne",
"doi-asserted-by": "crossref",
"first-page": "293",
"issue": "4",
"journal-title": "Trends Neurosci.",
"key": "10.1016/j.nexres.2026.101727_bib0073",
"volume": "42",
"year": "2019"
},
{
"article-title": "Neurosteroid hormone vitamin D and its utility in clinical nutrition",
"author": "Kalueff",
"first-page": "12",
"issue": "1",
"journal-title": "Curr. Opin. Clin. Nutr. Metab. Care",
"key": "10.1016/j.nexres.2026.101727_bib0074",
"volume": "10",
"year": "2007"
},
{
"DOI": "10.1055/s-0040-1722227",
"article-title": "Smell regions in patients with vitamin D deficiency: an MRI evaluation",
"author": "Şencan",
"doi-asserted-by": "crossref",
"first-page": "593",
"issue": "5",
"journal-title": "J. Neurol. Surg. B Skull. Base",
"key": "10.1016/j.nexres.2026.101727_bib0075",
"volume": "82",
"year": "2021"
},
{
"DOI": "10.4103/0972-6691.134223",
"article-title": "Role of vitamin D supplementation in allergic rhinitis",
"author": "Datt",
"doi-asserted-by": "crossref",
"first-page": "35",
"issue": "1",
"journal-title": "Indian J. Allergy, Asthma Immunol.",
"key": "10.1016/j.nexres.2026.101727_bib0076",
"volume": "28",
"year": "2014"
},
{
"DOI": "10.1016/j.jocn.2018.08.003",
"article-title": "Serum 25-hydroxyvitamin D3 level may be associated with olfactory dysfunction in de novo Parkinson's disease",
"author": "Kim",
"doi-asserted-by": "crossref",
"first-page": "131",
"journal-title": "J. Clin. Neurosci.",
"key": "10.1016/j.nexres.2026.101727_bib0077",
"volume": "57",
"year": "2018"
},
{
"DOI": "10.1016/j.mce.2011.05.014",
"article-title": "The effects of vitamin D on brain development and adult brain function",
"author": "Kesby",
"doi-asserted-by": "crossref",
"first-page": "121",
"issue": "1-2",
"journal-title": "Mol. Cell Endocrinol.",
"key": "10.1016/j.nexres.2026.101727_bib0078",
"volume": "347",
"year": "2011"
},
{
"DOI": "10.1023/A:1006932418220",
"article-title": "Distribution of 1,25-dihydroxyvitamin D3 receptor immunoreactivity in the rat olfactory system",
"author": "Glaser",
"doi-asserted-by": "crossref",
"first-page": "613",
"issue": "5",
"journal-title": "Cell. Mol. Neurobiol.",
"key": "10.1016/j.nexres.2026.101727_bib0079",
"volume": "19",
"year": "1999"
},
{
"DOI": "10.1016/j.bbr.2009.12.048",
"article-title": "The cholinergic system and Parkinson disease",
"author": "Bohnen",
"doi-asserted-by": "crossref",
"first-page": "564",
"issue": "2",
"journal-title": "Behav. Brain Res.",
"key": "10.1016/j.nexres.2026.101727_bib0080",
"volume": "221",
"year": "2011"
},
{
"DOI": "10.1016/j.bbr.2006.04.025",
"article-title": "Olfactory discrimination deficits in mice lacking the dopamine transporter or the D2 dopamine receptor",
"author": "Tillerson",
"doi-asserted-by": "crossref",
"first-page": "97",
"issue": "1",
"journal-title": "Behav. Brain Res.",
"key": "10.1016/j.nexres.2026.101727_bib0081",
"volume": "172",
"year": "2006"
},
{
"DOI": "10.1016/S1734-1140(13)71003-X",
"article-title": "Vitamin D and the central nervous system",
"author": "Wrzosek",
"doi-asserted-by": "crossref",
"first-page": "271",
"issue": "2",
"journal-title": "Pharmacol. Rep.",
"key": "10.1016/j.nexres.2026.101727_bib0082",
"volume": "65",
"year": "2013"
},
{
"DOI": "10.1016/j.neuroscience.2007.11.023",
"article-title": "Calcium-signaling networks in olfactory receptor neurons",
"author": "Klimmeck",
"doi-asserted-by": "crossref",
"first-page": "901",
"issue": "3",
"journal-title": "Neuroscience",
"key": "10.1016/j.nexres.2026.101727_bib0083",
"volume": "151",
"year": "2008"
},
{
"DOI": "10.7774/cevr.2025.14.e17",
"article-title": "Impact of vitamin D and zinc sufficiency on immune responses following COVID-19 vaccinations among healthcare workers",
"author": "Amadi",
"doi-asserted-by": "crossref",
"first-page": "162",
"issue": "2",
"journal-title": "Clin. Exp. Vaccine Res.",
"key": "10.1016/j.nexres.2026.101727_bib0084",
"volume": "14",
"year": "2025"
},
{
"DOI": "10.1016/S0030-6665(20)31695-9",
"article-title": "Disorders of smell and taste",
"author": "Estrem",
"doi-asserted-by": "crossref",
"first-page": "133",
"issue": "1",
"journal-title": "Otolaryngol. Clin. North Am.",
"key": "10.1016/j.nexres.2026.101727_bib0085",
"volume": "20",
"year": "1987"
},
{
"DOI": "10.1177/20417314221083414",
"article-title": "Restoration of olfactory dysfunctions by nanomaterials and stem cells-based therapies: current status and future perspectives",
"author": "Yoo",
"doi-asserted-by": "crossref",
"journal-title": "J. Tissue Eng.",
"key": "10.1016/j.nexres.2026.101727_bib0086",
"volume": "13",
"year": "2022"
},
{
"DOI": "10.1016/j.wjorl.2018.02.005",
"article-title": "Influence of medications on taste and smell",
"author": "Schiffman",
"doi-asserted-by": "crossref",
"first-page": "84",
"issue": "1",
"journal-title": "World J. Otorhinolaryngol. Head. Neck. Surg.",
"key": "10.1016/j.nexres.2026.101727_bib0087",
"volume": "4",
"year": "2018"
},
{
"DOI": "10.1111/sdi.12099",
"article-title": "Water-soluble vitamins in people with low glomerular filtration rate or on dialysis: a review",
"author": "Clase",
"doi-asserted-by": "crossref",
"first-page": "546",
"issue": "5",
"journal-title": "Semin. Dial.",
"key": "10.1016/j.nexres.2026.101727_bib0088",
"volume": "26",
"year": "2013"
},
{
"DOI": "10.1097/MD.0000000000021280",
"article-title": "Anosmia in the course of COVID-19: a case report",
"author": "Pissurno",
"doi-asserted-by": "crossref",
"issue": "31",
"journal-title": "Medicine",
"key": "10.1016/j.nexres.2026.101727_bib0089",
"volume": "99",
"year": "2020"
},
{
"article-title": "Novel protocol using a comprehensive training ‘N’ treatment (TNT) approach rapidly reverses olfactory and gustatory dysfunction in patients with acute loss of taste and smell induced by SARS-CoV-2 infection",
"author": "Young",
"journal-title": "Res. Sq.",
"key": "10.1016/j.nexres.2026.101727_bib0090",
"year": "2023"
},
{
"DOI": "10.1177/00034894221111093",
"article-title": "Tailored approach for persistent olfactory dysfunction after SARS-CoV-2 infection: a pilot study",
"author": "Sousa",
"doi-asserted-by": "crossref",
"first-page": "657",
"issue": "6",
"journal-title": "Ann. Otol. Rhinol. Laryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0091",
"volume": "132",
"year": "2023"
},
{
"article-title": "Treatment of pyroluric schizophrenia (malvaria) with large doses of pyridoxine and a dietary supplement of zinc",
"author": "Pfeiffer",
"first-page": "21",
"journal-title": "J. Appl. Nutr.",
"key": "10.1016/j.nexres.2026.101727_bib0092",
"volume": "26",
"year": "1974"
},
{
"DOI": "10.1007/s12078-022-09301-1",
"article-title": "Possible role of endocannabinoids in olfactory and taste dysfunctions in COVID-19 Patients and Volumetric Changes in the Brain",
"author": "Ergül",
"doi-asserted-by": "crossref",
"first-page": "135",
"issue": "2",
"journal-title": "Chemosens. Percept.",
"key": "10.1016/j.nexres.2026.101727_bib0093",
"volume": "15",
"year": "2022"
},
{
"DOI": "10.1002/alr.21790",
"article-title": "Effect of vitamin B12 deficiency on olfactory function",
"author": "Derin",
"doi-asserted-by": "crossref",
"first-page": "1051",
"issue": "10",
"journal-title": "Int. Forum. Allergy Rhinol.",
"key": "10.1016/j.nexres.2026.101727_bib0094",
"volume": "6",
"year": "2016"
},
{
"article-title": "Olfactory function and dysfunction",
"author": "Doty",
"first-page": "306",
"journal-title": "Head & Neck Surgery-Otolaryngology",
"key": "10.1016/j.nexres.2026.101727_bib0095",
"volume": "289",
"year": "2006"
},
{
"DOI": "10.1002/alr.22929",
"article-title": "International consensus statement on allergy and rhinology: Olfaction",
"author": "Patel",
"doi-asserted-by": "crossref",
"first-page": "327",
"issue": "4",
"journal-title": "Int. Forum. Allergy Rhinol.",
"key": "10.1016/j.nexres.2026.101727_bib0096",
"volume": "12",
"year": "2022"
},
{
"article-title": "Olfactory impairment",
"author": "Davidson",
"first-page": "71",
"issue": "1",
"journal-title": "West J. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0097",
"volume": "159",
"year": "1993"
},
{
"article-title": "Smell and taste disorders in primary care",
"author": "Malaty",
"first-page": "852",
"issue": "12",
"journal-title": "Am. Fam. Physician",
"key": "10.1016/j.nexres.2026.101727_bib0098",
"volume": "88",
"year": "2013"
},
{
"DOI": "10.1002/ccr3.5069",
"article-title": "Use of B-complex vitamins and olfactory training for treating COVID-19-related anosmia",
"author": "Vityala",
"doi-asserted-by": "crossref",
"issue": "11",
"journal-title": "Clin. Case Rep.",
"key": "10.1016/j.nexres.2026.101727_bib0099",
"volume": "9",
"year": "2021"
},
{
"DOI": "10.1002/(SICI)1097-4598(199810)21:10<1341::AID-MUS18>3.0.CO;2-4",
"article-title": "Axonal and demyelinating neuropathy with reversible proximal conduction block, an unusual feature of vitamin B12 deficiency",
"author": "Al-Shubaili",
"doi-asserted-by": "crossref",
"first-page": "1341",
"issue": "10",
"journal-title": "Muscle Nerve",
"key": "10.1016/j.nexres.2026.101727_bib0100",
"volume": "21",
"year": "1998"
},
{
"DOI": "10.1002/alr.21790",
"article-title": "Effect of vitamin B12 deficiency on olfactory function",
"author": "Derin",
"doi-asserted-by": "crossref",
"first-page": "1051",
"issue": "10",
"journal-title": "Int. Forum. Allergy Rhinol.",
"key": "10.1016/j.nexres.2026.101727_bib0101",
"volume": "6",
"year": "2016"
},
{
"article-title": "Relation between vitamin B12 levels and smell affection in COVID-19 patients",
"author": "Elsayad",
"issue": "4",
"journal-title": "Int. Arch. Otorhinolaryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0102",
"volume": "26",
"year": "2022"
},
{
"DOI": "10.1007/s00234-013-1306-y",
"article-title": "Diffusion tensor tractography and neuropsychological assessment in patients with vitamin B12 deficiency",
"author": "Gupta",
"doi-asserted-by": "crossref",
"first-page": "97",
"issue": "2",
"journal-title": "Neuroradiology",
"key": "10.1016/j.nexres.2026.101727_bib0103",
"volume": "56",
"year": "2014"
},
{
"DOI": "10.3945/ajcn.113.061549",
"article-title": "Cobalamin supplementation improves motor development and regurgitations in infants: results from a randomized intervention study",
"author": "Torsvik",
"doi-asserted-by": "crossref",
"first-page": "1233",
"issue": "5",
"journal-title": "Am. J. Clin. Nutr.",
"key": "10.1016/j.nexres.2026.101727_bib0104",
"volume": "98",
"year": "2013"
},
{
"DOI": "10.4103/1673-5374.220779",
"article-title": "Hyperhomocysteinemia induces injury in olfactory bulb neurons by downregulating Hes1 and Hes5 expression",
"author": "Zhang",
"doi-asserted-by": "crossref",
"first-page": "272",
"issue": "2",
"journal-title": "Neural Regen. Res.",
"key": "10.1016/j.nexres.2026.101727_bib0105",
"volume": "13",
"year": "2018"
},
{
"DOI": "10.3109/00207454.2015.1077331",
"article-title": "A retrospective study of 23 cases with subacute combined degeneration",
"author": "Li",
"doi-asserted-by": "crossref",
"first-page": "872",
"issue": "10",
"journal-title": "Int. J. Neurosci.",
"key": "10.1016/j.nexres.2026.101727_bib0106",
"volume": "126",
"year": "2016"
},
{
"DOI": "10.1002/ar.22736",
"article-title": "Olfactory system and demyelination",
"author": "Garcia-Gonzalez",
"doi-asserted-by": "crossref",
"first-page": "1424",
"issue": "9",
"journal-title": "Anat. Rec.",
"key": "10.1016/j.nexres.2026.101727_bib0107",
"volume": "296",
"year": "2013"
},
{
"DOI": "10.1016/j.jtemb.2006.01.006",
"article-title": "Zinc requirements and the risks and benefits of zinc supplementation",
"author": "Maret",
"doi-asserted-by": "crossref",
"first-page": "3",
"issue": "1",
"journal-title": "J. Trace Elem. Med. Biol.",
"key": "10.1016/j.nexres.2026.101727_bib0108",
"volume": "20",
"year": "2006"
},
{
"DOI": "10.3390/molecules29133130",
"article-title": "Zinc toxicity: understanding the limits",
"author": "Schoofs",
"doi-asserted-by": "crossref",
"first-page": "3130",
"issue": "13",
"journal-title": "Molecules",
"key": "10.1016/j.nexres.2026.101727_bib0109",
"volume": "29",
"year": "2024"
},
{
"DOI": "10.1146/annurev.bi.61.070192.004341",
"article-title": "Zinc proteins: enzymes, storage proteins, transcription factors, and replication proteins",
"author": "Coleman",
"doi-asserted-by": "crossref",
"first-page": "897",
"journal-title": "Annu. Rev. Biochem.",
"key": "10.1016/j.nexres.2026.101727_bib0110",
"volume": "61",
"year": "1992"
},
{
"DOI": "10.1016/j.jnutbio.2019.108240",
"article-title": "Micronutrients in autoimmune diseases: possible therapeutic benefits of zinc and vitamin D",
"author": "Wessels",
"doi-asserted-by": "crossref",
"journal-title": "J. Nutr. Biochem.",
"key": "10.1016/j.nexres.2026.101727_bib0111",
"volume": "77",
"year": "2020"
},
{
"DOI": "10.1097/01.mlg.0000191549.17796.13",
"article-title": "Intranasal zinc and anosmia: the zinc-induced anosmia syndrome",
"author": "Alexander",
"doi-asserted-by": "crossref",
"first-page": "217",
"journal-title": "Laryngoscope",
"key": "10.1016/j.nexres.2026.101727_bib0112",
"volume": "116",
"year": "2006"
},
{
"DOI": "10.3109/15360288.2012.676618",
"article-title": "A randomized, placebo controlled trial of oral zinc for chemotherapy-related taste and smell disorders",
"author": "Lyckholm",
"doi-asserted-by": "crossref",
"first-page": "111",
"issue": "2",
"journal-title": "J. Pain. Palliat. Care Pharmacother.",
"key": "10.1016/j.nexres.2026.101727_bib0113",
"volume": "26",
"year": "2012"
},
{
"DOI": "10.1001/archotol.1991.01870170065015",
"article-title": "Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center",
"author": "Deems",
"doi-asserted-by": "crossref",
"first-page": "519",
"issue": "5",
"journal-title": "Arch. Otolaryngol. Head Neck Surg.",
"key": "10.1016/j.nexres.2026.101727_bib0114",
"volume": "117",
"year": "1991"
},
{
"DOI": "10.1001/jama.1971.03190040028006",
"article-title": "Idiopathic hypogeusia with dysgeusia, hyposmia, and dysosmia. A new syndrome",
"author": "Henkin",
"doi-asserted-by": "crossref",
"first-page": "434",
"issue": "4",
"journal-title": "JAMA",
"key": "10.1016/j.nexres.2026.101727_bib0115",
"volume": "217",
"year": "1971"
},
{
"DOI": "10.1016/B978-0-12-366851-6.50011-9",
"article-title": "Idiopathic hypogeusia: a description of the syndrome and a single-blind study with zinc sulfate",
"author": "Schechter",
"doi-asserted-by": "crossref",
"first-page": "125",
"journal-title": "Int. Rev. Neurobiol.",
"key": "10.1016/j.nexres.2026.101727_bib0116",
"volume": "1",
"year": "1972"
},
{
"DOI": "10.1097/00000441-197611000-00006",
"article-title": "A double blind study of the effects of zinc sulfate on taste and smell dysfunction",
"author": "Henkin",
"doi-asserted-by": "crossref",
"first-page": "285",
"issue": "3",
"journal-title": "Am. J. Med. Sci.",
"key": "10.1016/j.nexres.2026.101727_bib0117",
"volume": "272",
"year": "1976"
},
{
"DOI": "10.1080/003655402_000028054",
"article-title": "The quinoxaline derivative caroverine in the treatment of sensorineural smell disorders: a proof-of-concept study",
"author": "Quint",
"doi-asserted-by": "crossref",
"first-page": "877",
"issue": "8",
"journal-title": "Acta Otolaryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0118",
"volume": "122",
"year": "2002"
},
{
"article-title": "Effect of zinc sulfate on sensorineural olfactory disorder",
"author": "Aiba",
"first-page": "202",
"journal-title": "Acta Otolaryngol. Suppl.",
"key": "10.1016/j.nexres.2026.101727_bib0119",
"volume": "538",
"year": "1998"
},
{
"DOI": "10.1089/acm.1999.5.57",
"article-title": "Evidence of functional zinc deficiency in Parkinson's disease",
"author": "Forsleff",
"doi-asserted-by": "crossref",
"first-page": "57",
"issue": "1",
"journal-title": "J. Altern. Complement. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0120",
"volume": "5",
"year": "1999"
},
{
"article-title": "Effects of zinc gluconate and 2 other divalent cationic compounds on olfactory function in mice",
"author": "Duncan-Lewis",
"first-page": "361",
"issue": "4",
"journal-title": "Comp. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0121",
"volume": "61",
"year": "2011"
},
{
"DOI": "10.1016/S0300-483X(03)00208-7",
"article-title": "Transport and subcellular distribution of intranasally administered zinc in the olfactory system of rats and pikes",
"author": "Persson",
"doi-asserted-by": "crossref",
"first-page": "97",
"issue": "2-3",
"journal-title": "Toxicology",
"key": "10.1016/j.nexres.2026.101727_bib0122",
"volume": "191",
"year": "2003"
},
{
"DOI": "10.1016/0006-8993(78)90460-2",
"article-title": "Denervation of the primary olfactory pathway in mice. V. Long-term effect of intranasal ZnSO4 irrigation on behavior, biochemistry and morphology",
"author": "Harding",
"doi-asserted-by": "crossref",
"first-page": "271",
"issue": "2",
"journal-title": "Brain Res.",
"key": "10.1016/j.nexres.2026.101727_bib0123",
"volume": "140",
"year": "1978"
},
{
"DOI": "10.1016/j.neuro.2016.12.003",
"article-title": "Zinc gluconate toxicity in wild-type vs. MT1/2-deficient mice",
"author": "Hsieh",
"doi-asserted-by": "crossref",
"first-page": "130",
"journal-title": "Neurotoxicology",
"key": "10.1016/j.nexres.2026.101727_bib0124",
"volume": "58",
"year": "2017"
},
{
"DOI": "10.1007/s12011-020-02546-5",
"article-title": "Olfactory disturbances as presenting manifestation among Egyptian patients with COVID-19: possible role of zinc",
"author": "Abdelmaksoud",
"doi-asserted-by": "crossref",
"first-page": "4101",
"issue": "11",
"journal-title": "Biol. Trace Elem. Res.",
"key": "10.1016/j.nexres.2026.101727_bib0125",
"volume": "199",
"year": "2021"
},
{
"DOI": "10.1002/lio2.513",
"article-title": "Intra-nasal zinc level relationship to COVID-19 anosmia and type 1 interferon response: A proposal",
"author": "Equils",
"doi-asserted-by": "crossref",
"first-page": "21",
"issue": "1",
"journal-title": "Laryngoscope Investig. Otolaryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0126",
"volume": "6",
"year": "2020"
},
{
"DOI": "10.1371/journal.ppat.1001176",
"article-title": "Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture",
"author": "te Velthuis",
"doi-asserted-by": "crossref",
"issue": "11",
"journal-title": "PLoS Pathog.",
"key": "10.1016/j.nexres.2026.101727_bib0127",
"volume": "6",
"year": "2010"
},
{
"DOI": "10.1016/j.amsu.2022.104062",
"article-title": "Role of natural products towards the SARS-CoV-2: a critical review",
"author": "Raman",
"doi-asserted-by": "crossref",
"journal-title": "Ann. Med. Surg.",
"key": "10.1016/j.nexres.2026.101727_bib0128",
"volume": "80",
"year": "2022"
},
{
"DOI": "10.1016/j.amsu.2022.103638",
"article-title": "Immunomodulatory effects of zinc and its impact on COVID-19 severity",
"author": "Dhawan",
"doi-asserted-by": "crossref",
"journal-title": "Ann. Med. Surg.",
"key": "10.1016/j.nexres.2026.101727_bib0129",
"volume": "77",
"year": "2022"
},
{
"DOI": "10.1007/s10787-023-01176-2",
"article-title": "COVID-19-induced neurological symptoms: focus on the role of metal ions",
"author": "Zhang",
"doi-asserted-by": "crossref",
"first-page": "611",
"issue": "2",
"journal-title": "Inflammopharmacology",
"key": "10.1016/j.nexres.2026.101727_bib0130",
"volume": "31",
"year": "2023"
},
{
"DOI": "10.1093/advances/nmz013",
"article-title": "The role of zinc in antiviral immunity",
"author": "Read",
"doi-asserted-by": "crossref",
"first-page": "696",
"issue": "4",
"journal-title": "Adv. Nutr.",
"key": "10.1016/j.nexres.2026.101727_bib0131",
"volume": "10",
"year": "2019"
},
{
"DOI": "10.1016/0891-5849(95)00017-R",
"article-title": "Alpha-lipoic acid as a biological antioxidant",
"author": "Packer",
"doi-asserted-by": "crossref",
"first-page": "227",
"issue": "2",
"journal-title": "Free Radic. Biol. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0132",
"volume": "19",
"year": "1995"
},
{
"key": "10.1016/j.nexres.2026.101727_bib0133",
"unstructured": "Nguyen H, Pellegrini MV, Gupta V. Alpha-lipoic acid. 2024 Jan 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 33231971."
},
{
"DOI": "10.1002/jnr.23289",
"article-title": "Effect of lipoic acid and α-glyceryl-phosphoryl-choline on astroglial cell proliferation and differentiation in primary culture",
"author": "Grasso",
"doi-asserted-by": "crossref",
"first-page": "86",
"issue": "1",
"journal-title": "J. Neurosci. Res.",
"key": "10.1016/j.nexres.2026.101727_bib0134",
"volume": "92",
"year": "2014"
},
{
"DOI": "10.1016/j.bbagen.2009.07.026",
"article-title": "Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential",
"author": "Shay",
"doi-asserted-by": "crossref",
"first-page": "1149",
"issue": "10",
"journal-title": "Biochim. Biophys. Acta",
"key": "10.1016/j.nexres.2026.101727_bib0135",
"volume": "1790",
"year": "2009"
},
{
"DOI": "10.2337/dc11-0503",
"article-title": "Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial",
"author": "Ziegler",
"doi-asserted-by": "crossref",
"first-page": "2054",
"issue": "9",
"journal-title": "Diabetes Care",
"key": "10.1016/j.nexres.2026.101727_bib0136",
"volume": "34",
"year": "2011"
},
{
"DOI": "10.1097/00005537-200211000-00031",
"article-title": "Lipoic acid in the treatment of smell dysfunction following viral infection of the upper respiratory tract",
"author": "Hummel",
"doi-asserted-by": "crossref",
"first-page": "2076",
"issue": "11",
"journal-title": "Laryngoscope",
"key": "10.1016/j.nexres.2026.101727_bib0137",
"volume": "112",
"year": "2002"
},
{
"DOI": "10.37290/ctnr2641-452X.19:172-175",
"article-title": "Alpha lipoic acid as a potential treatment for COVID-19 – a hypothesis",
"author": "Sayiner",
"doi-asserted-by": "crossref",
"first-page": "172",
"issue": "2",
"journal-title": "Curr. Top. Nutraceutical Res.",
"key": "10.1016/j.nexres.2026.101727_bib0138",
"volume": "19",
"year": "2020"
},
{
"DOI": "10.1017/S0022215120002455",
"article-title": "Olfactory epithelium histopathological findings in long-term coronavirus disease 2019 related anosmia",
"author": "Vaira",
"doi-asserted-by": "crossref",
"first-page": "1123",
"issue": "12",
"journal-title": "J. Laryngol. Otol.",
"key": "10.1016/j.nexres.2026.101727_bib0139",
"volume": "134",
"year": "2020"
},
{
"DOI": "10.3390/biomedicines11041109",
"article-title": "Parosmia COVID-19 related treated by a combination of olfactory training and ultramicronized PEA-LUT: a prospective randomized controlled trial",
"author": "Di Stadio",
"doi-asserted-by": "crossref",
"first-page": "1109",
"issue": "4",
"journal-title": "Biomedicines",
"key": "10.1016/j.nexres.2026.101727_bib0140",
"volume": "11",
"year": "2023"
},
{
"DOI": "10.1016/j.bjorl.2023.101356",
"article-title": "Alpha-lipoic acid does not improve olfactory training results in olfactory loss due to COVID-19: a double-blind randomized trial",
"author": "Figueiredo",
"doi-asserted-by": "crossref",
"issue": "1",
"journal-title": "Braz. J. Otorhinolaryngol.",
"key": "10.1016/j.nexres.2026.101727_bib0141",
"volume": "90",
"year": "2024"
},
{
"DOI": "10.1080/07315724.2008.10719732",
"article-title": "Evidence for anti-inflammatory effects of combined administration of vitamin E and C in older persons with impaired fasting glucose: impact on insulin action",
"author": "Rizzo",
"doi-asserted-by": "crossref",
"first-page": "505",
"issue": "4",
"journal-title": "J. Am. Coll. Nutr.",
"key": "10.1016/j.nexres.2026.101727_bib0142",
"volume": "27",
"year": "2008"
},
{
"DOI": "10.1155/2014/426740",
"article-title": "Vitamin C mitigates oxidative stress and tumor necrosis factor-alpha in severe community-acquired pneumonia and LPS-induced macrophages",
"author": "Chen",
"doi-asserted-by": "crossref",
"journal-title": "Mediators Inflamm.",
"key": "10.1016/j.nexres.2026.101727_bib0143",
"year": "2014"
},
{
"DOI": "10.3389/fimmu.2020.570122",
"article-title": "Immune-boosting, antioxidant and anti-inflammatory food supplements targeting pathogenesis of COVID-19",
"author": "Mrityunjaya",
"doi-asserted-by": "crossref",
"journal-title": "Front. Immunol.",
"key": "10.1016/j.nexres.2026.101727_bib0144",
"volume": "11",
"year": "2020"
},
{
"DOI": "10.2147/DDDT.S83144",
"article-title": "Effect of vitamin C on inflammation and metabolic markers in hypertensive and/or diabetic obese adults: a randomized controlled trial",
"author": "Ellulu",
"doi-asserted-by": "crossref",
"first-page": "3405",
"journal-title": "Drug Des. Devel. Ther.",
"key": "10.1016/j.nexres.2026.101727_bib0145",
"volume": "9",
"year": "2015"
},
{
"DOI": "10.1080/14767058.2017.1372413",
"article-title": "The effects of vitamin E supplementation on endometrial thickness, and gene expression of vascular endothelial growth factor and inflammatory cytokines among women with implantation failure",
"author": "Hashemi",
"doi-asserted-by": "crossref",
"first-page": "95",
"issue": "1",
"journal-title": "J. Matern. Fetal. Neonatal. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0146",
"volume": "32",
"year": "2019"
},
{
"DOI": "10.1016/j.freeradbiomed.2007.12.018",
"article-title": "Gamma-tocopherol supplementation alone and in combination with alpha-tocopherol alters biomarkers of oxidative stress and inflammation in subjects with metabolic syndrome",
"author": "Devaraj",
"doi-asserted-by": "crossref",
"first-page": "1203",
"issue": "6",
"journal-title": "Free Radic. Biol. Med.",
"key": "10.1016/j.nexres.2026.101727_bib0147",
"volume": "44",
"year": "2008"
},
{
"key": "10.1016/j.nexres.2026.101727_bib0148",
"unstructured": "Abdullah M, Jamil RT, Attia FN. Vitamin C (ascorbic acid). 2023 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 29763052."
},
{
"key": "10.1016/j.nexres.2026.101727_bib0149",
"unstructured": "Owen KN, Dewald O. Vitamin E toxicity. 2023 Feb 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 33232043."
},
{
"DOI": "10.1093/qjmed/hcaa341",
"article-title": "Rapid recovery of taste and smell in a patient with SARS-CoV-2 following convalescent plasma therapy",
"author": "Fisher",
"doi-asserted-by": "crossref",
"first-page": "319",
"issue": "5",
"journal-title": "QJM",
"key": "10.1016/j.nexres.2026.101727_bib0150",
"volume": "114",
"year": "2021"
},
{
"DOI": "10.1002/alr.22592",
"article-title": "Self-reported olfactory loss associates with outpatient clinical course in COVID-19",
"author": "Yan",
"doi-asserted-by": "crossref",
"first-page": "821",
"issue": "7",
"journal-title": "Int. Forum Allergy Rhinol.",
"key": "10.1016/j.nexres.2026.101727_bib0151",
"volume": "10",
"year": "2020"
},
{
"article-title": "Dietary approach for post-COVID treatment of olfactory loss",
"author": "Roy-Chowdhury",
"journal-title": "Integr. J. Med. Sci.",
"key": "10.1016/j.nexres.2026.101727_bib0152",
"volume": "8",
"year": "2021"
},
{
"DOI": "10.1021/cn500308h",
"article-title": "Vitamin C deficiency in the brain impairs cognition, increases amyloid accumulation and deposition, and oxidative stress in APP/PSEN1 and normally aging mice",
"author": "Dixit",
"doi-asserted-by": "crossref",
"first-page": "570",
"issue": "4",
"journal-title": "ACS Chem. Neurosci.",
"key": "10.1016/j.nexres.2026.101727_bib0153",
"volume": "6",
"year": "2015"
},
{
"DOI": "10.1093/chemse/24.2.211",
"article-title": "A method for maintaining odor-responsive adult rat olfactory receptor neurons in short-term culture",
"author": "Vargas",
"doi-asserted-by": "crossref",
"first-page": "211",
"issue": "2",
"journal-title": "Chem. Senses.",
"key": "10.1016/j.nexres.2026.101727_bib0154",
"volume": "24",
"year": "1999"
},
{
"DOI": "10.1021/acschemneuro.5b00106",
"article-title": "Ascorbate protects neurons against oxidative stress: a Raman microspectroscopic study",
"author": "Dutta",
"doi-asserted-by": "crossref",
"first-page": "1794",
"issue": "11",
"journal-title": "ACS Chem. Neurosci.",
"key": "10.1016/j.nexres.2026.101727_bib0155",
"volume": "6",
"year": "2015"
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