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Benefits of Nanocurcumin on Mortality in Patients with COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Shang et al., Journal of Integrative and Complementary Medicine, doi:10.1177/27683605251379004, Sep 2025
https://c19early.org/shang2.html
Mortality 53% Improvement Relative Risk Curcumin for COVID-19  Shang et al.  META ANALYSIS c19early.org Favorscurcumin Favorscontrol 0 0.5 1 1.5 2+
Curcumin for COVID-19
16th treatment shown to reduce risk in February 2021, now with p = 0.0000000061 from 28 studies.
No treatment is 100% effective. Protocols combine treatments.
6,100+ studies for 180 treatments. c19early.org
Systematic review and meta-analysis of six RCTs showing significantly lower COVID-19 mortality with nanocurcumin treatment.
5 meta analyses show significant improvements with curcumin for mortality1-5, hospitalization1,4, recovery3, and symptoms1.
Currently there are 28 curcumin for COVID-19 studies, showing 63% lower mortality [36‑78%], 80% lower ventilation [25‑95%], 78% lower ICU admission [-27‑96%], and 27% lower hospitalization [18‑34%].
risk of death, 53.0% lower, RR 0.47, p = 0.02.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Shang et al., 16 Sep 2025, peer-reviewed, 3 authors.
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