Oral Rinse to Reduced Expelled Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) During COVID-19 Infection

Xie et al., NCT04931004, NCT04931004, Feb 2022
24th treatment shown to reduce risk in May 2021, now with p = 0.024 from 8 studies.
Lower risk for viral clearance.
No treatment is 100% effective. Protocols combine treatments.
6,300+ studies for 210+ treatments. c19early.org
Meta Analysis
Estimated 90 patient hydrogen peroxide early treatment RCT with results not reported over 3 years after estimated completion.
2 hydrogen peroxide RCTs have results missing long after expected1,2
The trials report an estimated total of 140 patients.
Important missing comments or errors? Let us know.
Study covers chlorhexidine, cetylpyridinium chloride, and hydrogen peroxide.
Xie et al., 28 Feb 2022, Double Blind Randomized Controlled Trial, placebo-controlled, trial NCT04931004 (history).
Please send us corrections, updates, or comments. c19early involves the extraction of 200,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. IMA and WCH provide treatment protocols.
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