Melatonin, Vitamins and Minerals Supplements for the Treatment of Covid-19 and Covid-like Illness: Results of a Prospective, Randomised, Double-blinded Multicentre Study

Boukef et al., NCT05670444, NCT05670444, Feb 2023

Zinc for COVID-19

2nd treatment shown to reduce risk in July 2020, now with p = 0.00000013 from 40 studies, recognized in 23 countries.

No treatment is 100% effective.
Protocols combine treatments.

150 patient zinc early treatment RCT with results not reported over 3 years after completion.
4 zinc RCTs have results missing long after expected1-4
The trials report a total of 900 patients, with 1 trial having actual enrollment of 150, and the remainder estimated.
Study covers melatonin, vitamin C, vitamin D, and zinc.
Boukef et al., 28 Feb 2023, Double Blind Randomized Controlled Trial, placebo-controlled, Tunisia, trial NCT05670444 (history).