Supplementary Data — Proxalutamide reduces COVID-19 risk: real-time meta analysis of 4 studies

@CovidAnalysis, December 2025, Version 11V11
0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ McCoy (DB RCT) 80% 0.20 [0.01-4.13] death 0/134 2/134 censored, see details CS​1​ Improvement, RR [CI] Treatment Control McCoy (DB RCT) 97% 0.03 [0.00-0.47] ventilation 0/134 17/134 censored, see details CS​1​ McCoy (DB RCT) 91% 0.09 [0.03-0.27] hosp. 3/134 35/134 censored, see details CS​1​ Cadegiani (DB RCT) 63% 0.37 [0.02-8.85] death 0/75 1/102 Cadegiani (DB RCT) 90% 0.10 [0.01-1.84] ventilation 0/75 5/102 Cadegiani (DB RCT) 86% 0.14 [0.03-0.60] hosp. 2/75 19/102 Kintor (DB RCT) 67% 0.33 [0.01-8.16] death 0/365 1/365 Kintor (DB RCT) 50% 0.50 [0.15-1.65] hosp. 4/365 8/365 Kintor (DB RCT) 67% 0.33 [0.01-8.16] death 0/360 1/361 Kintor (DB RCT) 71% 0.29 [0.06-1.37] hosp. 2/360 7/361 Kintor (DB RCT) 67% 0.33 [0.01-8.16] death 0/346 1/347 Kintor (DB RCT) 92% 0.08 [0.01-0.79] hosp. 0/346 6/347 Kintor (DB RCT) 74% 0.26 [0.13-0.51] viral+ 365 (n) 365 (n) Cadegiani (DB RCT) 78% 0.22 [0.16-0.30] death 45/423 171/355 Cadegiani (DB RCT) 79% 0.21 [0.15-0.30] death 34/423 138/355 Cadegiani (DB RCT) 45% 0.55 [0.49-0.62] no recov. 423 (n) 355 (n) Cadegiani (DB RCT) 55% 0.45 [0.39-0.52] no recov. 423 (n) 355 (n) Cadegiani (DB RCT) 33% 0.67 [0.54-0.82] hosp. time 423 (n) 355 (n) Proxalutamide COVID-19 outcomes c19early.org December 2025 ​1​ CS: censored, see details Favors proxalutamide Favors control
Fig. S1. All outcomes.