A Retrospective Study of High-dose Intravenous Vitamin C in Critically Ill Covid-19 Patients
Cheah Saw Kian, Chiam Zye Wei, Shamin Mohd Saffian, Farida Hanim Islahudin, Muhammad Nordin M Saud
Indian Journal of Critical Care Medicine, doi:10.5005/jaypee-journals-10071-24667.4
Objectives High-dose intravenous vitamin C (HDIVC) has been investigated as the adjuvant therapy in critically ill Coronavirus Disease 2019 (COVID-19) patients, but the appropriate optimal doses are still unclear. This study aimed to compare the clinical outcomes of critically ill COVID-19 patients treated with 2 different dosing regimens of HDIVC (12g per day versus 6g per day).
References
Abobaker, Alzwi, Alraied, Overview of the Possible Role of Vitamin C in Management of Covid-19, Pharmacol Rep
Arvinte, Singh, Marik, Serum Levels of Vitamin C and Vitamin D in a Cohort of Critically Ill Covid-19 Patients of a North American Community Hospital Intensive Care Unit in May 2020: A Pilot Study, Med Drug Discov
Bonanad, García-Blas, Tarazona-Santabalbina, Sanchis, Bertomeu-González et al., The Effect of Age on Mortality in Patients with Covid-19: A Meta-Analysis with 611,583 Subjects, J Am Med Dir Assoc
Boretti, Banik, Intravenous Vitamin C for Reduction of Cytokines Storm in Acute Respiratory Distress Syndrome, PharmaNutrition
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