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All Studies   Meta Analysis    Recent:   

Countries which Primarily Use Antimalarial Drugs As COVID-19 Treatment See Slower Dynamic of Daily Deaths

Izoulet, M., SSRN, doi:10.2139/ssrn.3575899
Apr 2020  
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Mortality 85% Improvement Relative Risk HCQ for COVID-19  Izoulet et al.  LATE TREATMENT Is late treatment with HCQ beneficial for COVID-19? Retrospective 1,000,000 patients in multiple countries Lower mortality with HCQ (p=0.001) c19hcq.org Izoulet, M., SSRN, April 2020 FavorsHCQ Favorscontrol 0 0.5 1 1.5 2+
HCQ for COVID-19
1st treatment shown to reduce risk in March 2020
 
*, now with p < 0.00000000001 from 418 studies, recognized in 46 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
5,000+ studies for 104 treatments. c19hcq.org
Compares the dynamics of daily deaths in the 10 days following the 3rd death in countries using and not using [H]CQ, showing dramatically lower death in [H]CQ countries. This paper does not attempt to account for population age and other differences between the countries and recommends further study.
This study is excluded in the after exclusion results of meta analysis: excessive unadjusted differences between groups.
risk of death, 85.0% lower, RR 0.15, p < 0.001.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Izoulet et al., 21 Apr 2020, retrospective, multiple countries, preprint, 1 author, dosage not specified.
This PaperHCQAll
Abstract: d Countries which Primarily use Antimalarial Drugs as 5 ev iew e COVID-19 Treatment See Slower Dynamic of daily Deaths Maxime Izoulet, CEMI-EHESS, Paris.
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Late treatment
is less effective
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