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All Studies   Meta Analysis    Recent:   

Safety and Efficacy of Drugs Given Off-label for COVID-19

Fernandez-Tresguerres et al., NCT05596617, NCT05596617
Mar 2022  
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Melatonin for COVID-19
11th treatment shown to reduce risk in December 2020
 
*, now with p = 0.0000002 from 18 studies.
Lower risk for mortality, ventilation, and recovery.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,800+ studies for 98 treatments. c19early.org
335 patient melatonin late treatment study with results not reported over 2 years after completion.
3 melatonin RCTs have results missing long after expected1-3
The trials report a total of 268 patients, with 2 trials having actual enrollment of 168, and the other estimated.
Fernandez-Tresguerres et al., 31 Mar 2022, Spain, trial NCT05596617 (history).
This PaperMelatoninAll
Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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