Supplementary Data — Cetylpyridinium Chloride reduces COVID-19 risk: real-time meta-analysis of 4 studies

c19early.org

October 2026

Cetylpyridinium chloride COVID-19 outcomes

StudyImprovementRR · 95% CIOutcomeTreatmentControlRelative Risk

Bonn (DB RCT)85%0.15 · 0.01–2.74viral load6 (n)9 (n)Short term viral CT¹ Gansky (DB RCT)60%0.40 · 0.02–7.68no recov.0/31/6AMPoL Ponphaib.. (DB RCT)36%0.64 · 0.46–0.89no recov.25/5342/57CT¹ Ponphaib.. (DB RCT)24%0.76 · 0.64–0.89no recov.43/5955/57CT¹ Ponphaib.. (DB RCT)14%0.86 · 0.77–0.97no recov.50/5956/57CT¹ Ponphaib.. (DB RCT)30%0.70 · 0.59–0.84no recov.40/5955/57CT¹ Rengifo (DB RCT)68%0.32 · 0.01–7.20hosp.0/121/11CT¹ Rengifo (DB RCT)83%0.17 · 0.02–1.20viral+1/125/10CT¹

00.511.52+

¹ CT: study uses combined treatment

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← CPC
reduces riskCPC
increases risk →

Fig. S1. All outcomes.