Neither Metformin nor Ursodeoxycholic Acid Effectively Treats Postacute Sequelae of COVID-19
et al., Annals of Internal Medicine, doi:10.7326/ANNALS-25-04883, Mar 2026
Metformin for COVID-19
3rd treatment shown to reduce risk in
July 2020, now with p < 0.00000000001 from 110 studies.
Lower risk for mortality, ventilation, ICU, hospitalization, progression, recovery, and viral clearance.
No treatment is 100% effective. Protocols
combine treatments.
6,400+ studies for
210+ treatments. c19early.org
|
RCT 396 patients with existing long COVID, showing no significant benefit with metformin or UDCA.
Study covers metformin and ursodeoxycholic acid.
Lim et al., 3 Mar 2026, Double Blind Randomized Controlled Trial, placebo-controlled, peer-reviewed, 12 authors.
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Late treatment
is less effective
is less effective
