Summary of COVID-19 tradipitant studies

1. Polymeropoulos et al., ODYSSEY: A Randomized, Double-blind, Placebo-controlled Study to Investigate the Efficacy of Tradipitant in Treating Inflammatory Lung Injury and Improving Clinical Outcomes Associated With Severe or Critical COVID-19 Infection

145 patient tradipitant late treatment RCT: 36% higher mortality (p=0.41) and no change in improvement.
RCT 145 severe/critical COVID-19 patients in the USA, showing no significant difference with tradipitant treatment.
Mar 2024, NCT04326426, https://clinicaltrials.gov/study/NCT04326426, https://c19p.org/polymeropoulos