Summary of COVID-19 rNAPc2 studies
Studies
Meta Analysis
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RCT 160 hospitalized COVID-19 patients showing no significant improvements with rNAPc2 (recombinant nematode anticoagulant protein c2) vs. heparin.
Aug 2023, Arteriosclerosis, Thrombosis, and Vascular Biology, https://www.ahajournals.org/doi/10.1161/ATVBAHA.122.318748, https://c19p.org/hess2
1. Hess et al., Novel Tissue Factor Inhibition for Thromboprophylaxis in COVID-19: Primary Results of the ASPEN-COVID-19 Trial
156 patient rNAPc2 late treatment RCT: 65% higher mortality (p=0.32).RCT 160 hospitalized COVID-19 patients showing no significant improvements with rNAPc2 (recombinant nematode anticoagulant protein c2) vs. heparin.
Aug 2023, Arteriosclerosis, Thrombosis, and Vascular Biology, https://www.ahajournals.org/doi/10.1161/ATVBAHA.122.318748, https://c19p.org/hess2
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