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All Studies   Meta Analysis    Recent:   

The association between B vitamins and the risk of COVID-19

Darand et al., British Journal of Nutrition, doi:10.1017/S0007114522003075
Nov 2022  
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Retrospective 9,189 adults showing no significant relationship between vitamin B9 intake and COVID-19 cases.
Darand et al., 9 Nov 2022, retrospective, Iran, peer-reviewed, 6 authors.
This PaperVitamin B9All
{ 'DOI': '10.1017/s0007114522003075', 'ISSN': ['0007-1145', '1475-2662'], 'URL': 'http://dx.doi.org/10.1017/S0007114522003075', 'abstract': '<jats:title>Abstract</jats:title>\n' '\t <jats:p>The fast spread of the coronavirus disease 2019 (COVID-19) epidemic and its high ' 'mortality were quickly noticed by the health community. B vitamins are essential ' 'micronutrients for the body with antioxidant, anti-inflammatory and immune-regulating ' 'properties. The present study can provide a comprehensive picture of the associations between ' 'B vitamins and COVID-19 incidence. This study was undertaken on 9189 adult participants of ' 'the Yazd Health Study (YaHS) and Taghzieh Mardom-e-Yazd (TAMIZ) study aged 20 to 69 years. ' 'Data on dietary intakes were obtained using a validated FFQ. Multivariable logistic ' 'regression analysis was used to evaluate the association between B vitamins and COVID-19. Our ' 'findings indicated that participants in the fourth quartile of vitamin ' 'B<jats:sub>5</jats:sub> intake compared with the first quartile had a protective effect ' 'against COVID-19 (OR: 0·53, 95 % CI 0·28, 0·99, <jats:italic>P</jats:italic>-trend = 0·02) ' 'after adjustment for all possible confounds in model 3. In addition, participants in the ' 'third quartile of vitamin B<jats:sub>12</jats:sub> intake compared with the first quartile ' '(OR: 0·63, 95 % CI 0·40, 0·98, <jats:italic>P</jats:italic>-trend = 0·11) had fewer odds of ' 'COVID-19 after full adjustments for confounders. Our findings indicated no significant ' 'relationship between dietary intake of vitamin B<jats:sub>1</jats:sub>, ' 'B<jats:sub>2</jats:sub>, B<jats:sub>3</jats:sub>, B<jats:sub>9</jats:sub> and B-complex and ' 'COVID-19. A higher intake of vitamin B<jats:sub>5</jats:sub> could reduce the odds of ' 'COVID-19 by 47 %, and a moderate intake of vitamin B<jats:sub>12</jats:sub> had a protective ' 'effect on COVID-19. Although our study has promising results, stronger clinical studies are ' 'needed.</jats:p>', 'alternative-id': ['S0007114522003075'], 'assertion': [ { 'group': {'label': 'Copyright and Licensing', 'name': 'copyright_and_licensing'}, 'label': 'Copyright', 'name': 'copyright', 'value': '© The Author(s), 2022. 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