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c19early.org COVID-19 treatment researchProxalutamideProxalutamide (more..)
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Proxalutamide reduces COVID-19 risk: real-time meta analysis of 4 studies

Covid Analysis, Jun 2025
https://c19early.org/caxmeta.html
Significantly lower risk is seen for mortality, ventilation, hospitalization, recovery, and viral clearance. 4 studies from 2 independent teams in 2 countries show significant benefit.
Meta analysis using the most serious outcome reported shows 78% [70‑83%] lower risk. Results are similar for peer-reviewed studies. Currently all studies are RCTs.
Control Proxalutamide
Studies to date are from only 2 different groups.
No treatment is 100% effective. Protocols combine safe and effective options with individual risk/benefit analysis and monitoring. All data and sources to reproduce this analysis are in the appendix.
Zheng et al. present another meta analysis for proxalutamide, showing significant improvements for mortality, mechanical ventilation, hospitalization, and clinical improvement.
Covid Analysis et al., Jun 2025, preprint, 1 author.
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Please send us corrections, updates, or comments. c19early involves the extraction of 200,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. IMA and WCH provide treatment protocols.
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