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All Studies   Meta Analysis    Recent:   

On the relationship between androgen-deprivation therapy for prostate cancer and risk of infection by SARS-CoV-2

Caffo et al., Annals of Oncology, doi:10.1016/j.annonc.2020.06.005
Oct 2020  
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5th treatment shown to reduce risk in August 2020
 
*, now known with p = 0.000000043 from 50 studies.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,800+ studies for 60+ treatments. c19early.org
Retrospective study of 1,949 metastatic prostate cancer patients on androgen deprivation therapy in Italy. The study found a 1.8% SARS-CoV-2 infection rate and 30.6% mortality among infected patients. Patients were elderly with metastatic castrate-resistant disease, which may explain the high mortality rate. There was no control group, so no conclusions can be made about any potential protective or harmful effect of ADT on COVID-19 infection risk or outcomes.
Caffo et al., 31 Oct 2020, retrospective, Italy, peer-reviewed, 20 authors. Contact: mariaadoracion.romaguera@ssib.es.
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