Statistically significant lower risk is seen for mortality, hospitalization, and recovery. 6 studies from 5 independent teams in 5 countries show significant improvements.
Meta analysis using the most serious outcome reported shows 43% [24‑57%] lower risk. Results are similar for Randomized Controlled Trials and peer-reviewed studies. Early treatment is more effective than late treatment.
SARS-CoV-2 requires acidic pH for fusion1. Alkalinization of the respiratory mucosa may reduce risk.
No treatment or intervention is 100% effective. All practical, effective, and safe means should be used based on risk/benefit analysis. Multiple treatments are typically used in combination, and other treatments may be more effective. We also present an analysis covering other alkalinization treatments2. Sodium Bicarbonate may affect the natural microbiome, especially with prolonged use.
All data to reproduce this paper and sources are in the appendix. Shafiee et al. present another meta analysis for sodium bicarbonate, showing significant improvements for mortality and recovery.
Covid Analysis et al., Oct 2024, preprint, 1 author.
