Early Treatment of Vulnerable Individuals With Non-Severe SARS-CoV-2 Infection: A Multi-Arm Multi-Stage Randomized Trial (MAMS) to Evaluate the Effectiveness of Several Specific Treatments in Reducing the Risk of Clinical Worsening or Death in Sub-Saharan Africa (COVERAGE-Africa)

Marcy et al., NCT04920838, COVERAGE-A, NCT04920838

Aug 2023

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Estimated 600 patient acetaminophen early treatment RCT with results expected soon (estimated completion over 2 months ago). Acetaminophen is also known as paracetamol, Tylenol, Panadol, Calpol, Tempra, Calprofen, Doliprane, Efferalgan, Grippostad C, Dolo, Acamol, Fevadol, Crocin, and Perfalgan.

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This study includes nitazoxanide, budesonide, and acetaminophen.

Marcy et al., 1 Aug 2023, Randomized Controlled Trial, multiple countries, trial NCT04920838 (history) (COVERAGE-A).

Contact: olivier.marcy@u-bordeaux.fr, anthony.lhostellier@u-bordeaux.fr, armelpoda@yahoo.fr, sondoapoline@yahoo.fr.

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