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All Studies   Meta Analysis    Recent:   

Early Treatment of Vulnerable Individuals With Non-Severe SARS-CoV-2 Infection: A Multi-Arm Multi-Stage Randomized Trial (MAMS) to Evaluate the Effectiveness of Several Specific Treatments in Reducing the Risk of Clinical Worsening or Death in Sub-Saharan Africa (COVERAGE-Africa)

Marcy et al., NCT04920838, COVERAGE-A, NCT04920838
Aug 2023  
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Budesonide for COVID-19
18th treatment shown to reduce risk in April 2021
 
*, now with p = 0.0000011 from 15 studies, recognized in 8 countries.
No treatment is 100% effective. Protocols combine treatments. * >10% efficacy, ≥3 studies.
4,300+ studies for 77 treatments. c19early.org
Estimated 600 patient budesonide early treatment RCT with results not reported over 10 months after estimated completion.
4 budesonide RCTs have results missing long after expected1-4
The trials report a total of 916 patients, with 1 trial having actual enrollment of 146, and the remainder estimated.
Study covers nitazoxanide, budesonide, and acetaminophen.
Marcy et al., 1 Aug 2023, Randomized Controlled Trial, multiple countries, trial NCT04920838 (history) (COVERAGE-A). Contact: olivier.marcy@u-bordeaux.fr, anthony.lhostellier@u-bordeaux.fr, armelpoda@yahoo.fr, sondoapoline@yahoo.fr.
This PaperBudesonideAll
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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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