Nutritional deficiencies that may predispose to long COVID

Schloss et al., Inflammopharmacology, doi:10.1007/s10787-023-01183-3

Mar 2023

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Review of 22 nutritional factors that have been linked to COVID-19 outcomes, the role of nutrients in COVID-19 infection, and the prevalence of multiple nutritional deficiencies in the population.

See Yuan et al. for another review covering N-acetylcysteine for COVID-19.

Important missing comments or errors? Let us know.

Study covers N-acetylcysteine, vitamin C, vitamin D, and zinc.

1. Yuan et al., The role of cell death in SARS-CoV-2 infection, Signal Transduction and Targeted Therapy, doi:10.1038/s41392-023-01580-8.nature.com, doi.org.

Schloss et al., 15 Mar 2023, peer-reviewed, 1 author.

This Paper N-acetylcys..All

Nutritional deficiencies that may predispose to long COVID

John V Schloss

Inflammopharmacology, doi:10.1007/s10787-023-01183-3

Multiple nutritional deficiencies (MND) confound studies designed to assess the role of a single nutrient in contributing to the initiation and progression of disease states. Despite the perception of many healthcare practitioners, up to 25% of Americans are deficient in five-or-more essential nutrients. Stress associated with the COVID-19 pandemic further increases the prevalence of deficiency states. Viral infections compete for crucial nutrients with immune cells. Viral replication and proliferation of immunocompetent cells critical to the host response require these essential nutrients, including zinc. Clinical studies have linked levels of more than 22 different dietary components to the likelihood of COVID-19 infection and the severity of the disease. People at higher risk of infection due to MND are also more likely to have long-term sequelae, known as Long COVID.

Declarations Conflict of interest The author declares that he has no conflict of interest, financial or otherwise. Consent for publication Not applicable.

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Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.

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