APD COVID-19 studies.
Recent:da Silva Santos Brito-Reia Poleti.
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Jun 7 |
(Preprint) (meta analysis) | APD for COVID-19: real-time meta analysis of 3 studies |
| Statistically significant improvements are seen for hospitalization and recovery. 2 studies from 2 independent teams (both from the same country) show statistically significant improvements in isolation (1 for the most serious outcome)... | ||
Dec 8 2021 |
et al., Journal of Evidence-Based Dental Practice, doi:10.1016/j.jebdp.2022.101777 (date from earlier preprint) | Use of mouthwash and dentifrice containing antimicrobial phthalocyanine derivative for the reduction of clinical symptoms of COVID-19: A randomized triple-blinded clinical trial |
| 29% improved recovery [p=0.02]. RCT 500 patients in Brazil, showing improved recovery with a phthalocyanine derivative mouthwash and toothpaste. Toothbrushing for 2 minutes, three times per day, and gargling/rising (5ml) for one minute, three times a day, for 7 days. | ||
Nov 15 2021 |
et al., German Medical Science GMS Publishing House, doi:10.3205/dgkh000426 (date from earlier preprint) | Population-based virucidal phthalocyanine gargling/rinsing protocol to reduce the risk of coronavirus disease-2019: a community trial |
| 54% fewer cases [p=0.08]. Comparison of two similar communities in Brazil, with one using a phthalocyanine derivative mouthwash, suggesting efficacy of the treatment in lowering COVID-19 cases. There was 54% lower risk of confirmed cases during the intervention in.. | ||
Oct 7 2021 |
et al., Scientific Reports, doi:10.1038/s41598-021-99013-5 | Beneficial effects of a mouthwash containing an antiviral phthalocyanine derivative on the length of hospital stay for COVID-19: randomised trial |
| 85% lower mortality [p=0.23], 92% lower ICU admission [p=0.02], and 54% lower hospitalization [p=0.03]. RCT 41 patients in Brazil, 20 treated with a phthalocyanine derivative mouthwash, showing shorter hosptalization and lower ICU admission with treatment. One minute gargling/rinsing 5 times per day. | ||
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